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A study observed that the levels of endothelial progenitor cells and vascular inflammation in patients treated for 24 weeks using Darunavir were indistinguishable from non-infected patients, while those exposed to Rilpivirine showed signs to endothelial cell dysfunction (Echeverria et al

J Cell Biol 113: 13311340 CummingsBS,AngelesR,McCauleyRB,LashLH (2000) Role of voltagedependent anion channels in glutathione transport into yeast mitochondria

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Only the sponsor's validated data can confirm both microbiological and chemical in-use stability for a specific IMP formulation